99% Fluconazole CAS 86386-73-4

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Lub npe tshuaj:Fluconazole

Lwm lub npe:2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol

CAS Nr:.86386-73-4

Purity:99%

Molecular Formula:C13H12F2N6O

Molecular Luj:306.27 Nws

Txheem:USP/BP/EP/CP/JP

Chemical Properties:Dawb mus rau dawb crystalline hmoov, me ntsis txawv tsw, iab saj.Soluble nyob rau hauv glacial acetic acid, methanol los yog ethanol, hardly soluble nyob rau hauv dej, yuav luag insoluble nyob rau hauv ether.Nws yog ib qho tshuaj fluorinated triazole broad-spectrum antifungal tshuaj, cov tshuaj tua kab mob zoo ib yam li ketoconazole, ua haujlwm ntev, zoo rau kev sib sib zog nqus kab mob fungal tshuaj, muaj zog tiv thaiv kab mob, thiab kev nqus ntawm qhov ncauj.Feem ntau siv rau candidiasis thiab cryptococcosis, kuj zoo rau oropharyngeal candidiasis hauv cov neeg mob qog noj ntshav.

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Fluconazole yog fluorinated triazole tshuaj tiv thaiv kab mob uas muaj cov kab mob zoo sib xws rau ketoconazole thiab muaj zog tiv thaiv kab mob ntau dua li ketoconazole.Nws cov txheej txheem ntawm kev ua haujlwm yog inhibit ergosterol synthase, ib qho tseem ceeb ntawm cov kab mob fungal, thaiv ergosterol synthesis, rhuav tshem kev ncaj ncees ntawm cov phab ntsa ntawm tes, thiab inhibit nws txoj kev loj hlob thiab kev loj hlob.

Cov khoom muaj zog tiv thaiv kab mob tiv thaiv Candida albicans, Microsporum, Cryptococcus neoformans, Epidermophyton thiab Histoplasma capsulatum.Nws yog absorbed zoo ntawm qhov ncauj, dav dav hauv lub cev, thiab tuaj yeem nkag mus rau hauv cov kua cerebrospinal.Clinically, nws yog tsuas yog siv rau qhov chaw mos candidiasis, thrush, atrophic qhov ncauj candidiasis, fungal meningitis, pulmonary fungal kab mob, kab mob plab, kab mob urinary ib ntsuj av thiab kab mob ntawm daim tawv nqaij fungal.